The number of measles cases from the outbreak linked to Disneyland has now risen to at least 98. But measles remains extremely rare in the United States.

The rest of the world hasn't been so fortunate. Last year roughly 250,000 people came down with measles; more than half of them died.

Currently the Philippines is experiencing a major measles outbreak that sickened 57,000 people in 2014. China had twice that many cases, although they were more geographically spread out. Major outbreaks were also recorded in Angola, Brazil, Ethiopia, Indonesia and Vietnam.

Measles causes an intense fever, coughing, watery eyes and a signature full-body rash. The disease is rarely fatal in developed nations with modern health care systems but can cause brain damage and permanent hearing loss.

Once the virus starts spreading among kids who haven't been immunized, it's very difficult to stop.

A Vietnamese boy is treated for measles in a state-run hospital in April 2014.

A Vietnamese boy is treated for measles in a state-run hospital in April 2014.

AFP/Getty Images

"The measles virus is probably the most contagious infectious disease known to mankind," says Stephen Cochi, a senior adviser with the Centers for Disease Control and Prevention's global immunization division.

Cochi's team tracks flare-ups of measles around the world. He says the current outbreak in the Philippines was sparked by Typhoon Haiyan, which battered the island nation late in 2013, killing more than 6,000 and hampering vaccination efforts. Cases started to multiply first in the storm-ravaged parts of the country.

"Then the virus spread to metro Manila and then other parts of the Philippines," he says. "That virus ... from the Philippines has spread all over the world, to the Middle East, to other parts of Asia, to the United States and Europe."

Some of the people who've caught measles in the current Southern California outbreak have the same strain of the virus that's circulating in the Philippines. The CDC has not yet pinpointed the origin of the first case at Disneyland.

These are the 15 countries with the highest number of cases. The U.S. ranks lower but is listed for comparison.

These are the 15 countries with the highest number of cases. The U.S. ranks lower but is listed for comparison.

*EU number is from European Center for Disease Prevention and Control and is the number of reported cases October 2013 to September 2014. All other data are from cases reported to WHO in 2014

From his experience tracking previous measles outbreaks in the U.S., Cochi says the source was probably an American.

"It's really traveling Americans who are unvaccinated, then return to the United States with the measles virus, that are causing most of the measles in the U.S. currently," he says.

Cochi adds that someone infected with measles may be contagious for 24 to 48 hours before feeling sick. So a returning traveler could spread the disease and not even know it. And because measles is circulating all over the world, a traveler could pick it up almost anywhere. Even the European Union recorded several thousand cases last year.

Part of the reason measles drives public health officials crazy is that it's a people problem. Humans are its only host. As long as the virus can find new unvaccinated populations, it can reproduce, survive and spread. But if immunization rates were boosted around the world, measles wouldn't be able to keep jumping to new hosts. Then the disease would disappear.

One of the groups working to achieve that high immunity around the globe is the International Medical Corps.

Paul Robinson with the group says actually immunizing a child against measles is easy and cheap. Their biggest challenge is reaching children after disasters and in war-torn countries.

"The children under 5 are very vulnerable to measles," Robinson says. They're the primary target of vaccination campaigns. "It takes just a few days to get them vaccinated but it also takes a very short time for the virus to kill them."

Prior to the widespread use of measles vaccines in the 1980s, there were more than 4 million cases around the globe every year. That number has been cut significantly to roughly a quarter of a million. But measles is still out there, and as Cochi at the CDC points out, the virus is just a plane ride away from the United States.

Copyright 2015 NPR. To see more, visit http://www.npr.org/.

Transcript

ROBERT SIEGEL, HOST:

The number of measles cases linked to a recent outbreak at Disneyland has now risen to at least 98. Even so, measles remains extremely rare in the United States. As NPR's Jason Beaubien reports, that's not the case in many other parts of the world.

JASON BEAUBIEN, BYLINE: Measles is a major public health problem across the developing world. The number of cases globally isn't as high as say, HIV or malaria, but in poor countries with less than ideal health care systems, measles is a killer. Last year of the roughly 250,000 cases around the world, half of them died. Measles causes an intense fever, coughing, watery eyes and a signature, full-body rash. It can also cause brain damage and permanent hearing loss. And once the virus starts spreading among kids who haven't been immunized, it's very difficult to stop.

STEVE COCHI: The measles virus is probably the most contagious infectious disease known to mankind.

BEAUBIEN: Steve Cochi is with the Centers for Disease Control and Prevention's Global Immunization Division. His team tracks flare-ups of measles around the world. Currently one of the biggest is in the Philippines, which generated almost 60,000 cases last year. Cochi says measles started spreading widely there after the country was battered by Typhoon Haiyan late in 2013.

COCHI: That virus incidentally from the Philippines has spread all over the world to the Middle East, to other parts of Asia, to the United States and to Europe.

BEAUBIEN: The CDC is still investigating the Disneyland outbreak and has not yet declared its exact source. From earlier U.S. cases however, Cochi says, surprisingly the source is usually not a foreign visitor.

COCHI: It's really traveling Americans who are unvaccinated then return to the United States with the measles virus that are causing most of the measles in the U.S., currently.

BEAUBIEN: There's a couple of issues here. First, travelers can be infected with measles and contagious before they feel sick. Second, there's measles just about everywhere in the world. Besides, the Philippines, China, Brazil, Ethiopia and Vietnam all had significant outbreaks last year. Even the European Union recorded several thousand cases. Part of the reason measles drives public health officials crazy is that it's a people problem. Humans are its only hosts. As long as the virus can find new, unvaccinated populations, it can reproduce, survive and spread some more.

COCHI: So if one can achieve high immunity throughout the world against measles, one can wipe out the disease.

BEAUBIEN: One of the groups working to achieve that high immunity around the globe is the International Medical Corps. Paul Robinson with the group says, actually, immunizing a child against measles is easy and cheap. Their biggest challenge is reaching children in post-disaster and war-torn countries, but Robinson believes it's very important that they do.

PAUL ROBINSON: The children under 5 are very vulnerable to measles. And it takes just a few days to get them to be vaccinated, but it also takes a very short time for the virus to kill them.

BEAUBIEN: Prior to the widespread use of measles vaccine in the 1980s, there were more than four million cases of the disease around the globe every year. That number has been cut significantly to roughly a quarter-of-a-million cases a year. But measles is still out there, and as Cochi at the CDC points out, the virus is just a plane ride away from the United States. Jason Beaubien, NPR News. Transcript provided by NPR, Copyright NPR.

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