The guitarist has played with Charlie Sexton, Roger Waters and Eric Clapton, but his latest music is influenced by trips through North Africa and India.
They'll be joined by Yes, Electric Light Orchestra and Joan Baez in the performer category. Chic maestro and David Bowie producer Nile Rodgers will receive an award for musical excellence.
The two-part video for "u" and "For Sale?" tackles issues of race and mental health, as well as the contradictions Lamar faces as a result of his own success.