The speech said to be by Abu Bakr al-Baghdadi rallies supporters while ISIS has steadily lost its territorial claims. It's the first such audio released since November last year.
Chaos around expected airport closures was the first sign of the strong reaction and backlash Iraqi Kurds are facing after they voted this week to split-off from Iraq.
Iraq's Kurdish region has overwhelmingly voted in favor of independence. Now the Iraqi government says it will block international flights to and from the region's airports in retaliation.
Iraqi Kurds voted on Monday in a referendum on whether to seek independence from Iraq. Neighboring countries worry an independent Kurdistan could destabilize the region.
The vote is seen as a way to signal the ethnic minority's desire for self-determination, despite strong opposition from regional and international powers. Turnout reportedly was high.
Monday's referendum for voters in Iraq's Kurdish region asks whether the Kurds should break away to form their own country. Iran and Turkey are watching the vote closely.
Iraq's Kurdistan region is scheduled to hold a referendum on independence on Monday, despite warnings from the U.S., the U.N. and neighboring countries.
The U.S., Turkey, Iran and others want Iraq's Kurds to cancel an independence vote set for Monday. Most Iraqi Kurds want their own country, which could prompt Kurds in other countries to follow suit.
In his first speech to the United Nations General Assembly, President Trump will defend his "America First" creed as a basis for countries to cooperate without losing sight of their own self-interest.