Underlying issues such as poverty and chronic disease make the South particularly vulnerable. The region is also at high risk for natural disasters at a time when emergency resources are stretched.
Officials fear that the growing number of COVID-19 cases could exceed the city's hospital capacity. As of noon Thursday, New Orleans had seen 11.8 deaths per 100,000 residents.
Rapid shutdowns to stem the coronavirus have delivered an unprecedented blow to restaurants around the U.S. Many are quickly running out of cash and their workers are losing their jobs.
In New Orleans, arguably the most far-out pre-Mardi Gras parade is staged by the Intergalactic Krewe of Chewbacchus: home to "revelrous Star Wars freaks, Trekkies, Whovians... and all super-nerds."
Record flooding on the Mississippi River sent too much fresh water into the Gulf of Mexico, killing oysters and crippling other seafood harvests that depend on saltwater to survive.
A tropical storm will bring gusty winds to the area, threatening the stability of two towering cranes that remain unstable following last weekend's disaster.
Sarah Broom's childhood house is the fulcrum for her memoir about her large and complex family. But perhaps more important, it stands in for the countless ways America has failed African Americans.