There's little evidence that vice presidential picks help candidates at the top of the ticket win a state. What nominees try to aim for often is balance.
President Obama plans to ask Congress for $755 million in cancer-research funding in his 2017 budget. That's in addition to $195 million already approved in 2016.
After strong debate performances by Clinton and Sanders, it's harder to see where the vice president would fit into the field. And that may be a welcome relief for a still-grieving Biden.
The vice president's popularity has tracked closely to Obama's during their administration, and it's risen as he explores a White House bid. But the realities of a campaign could bring it back down.
Speaking candidly about the death of his son, the vice president was authentic and raw. If he does run, it's that trait that could make him a dangerous challenger to Hillary Clinton.
History hasn't been kind to late presidential entrants. But with the vice president's name recognition and position, his campaign could break the mold and challenge and sharpen Hillary Clinton.