His three-day trip was intended to promote religious fraternity and diversity, at a time when long-established Christian communities in the Middle East are dwindling.
The pope brought a tablet to his usual Sunday address, as he announced the ClickToPray app for communal prayer around the world, with a call for young Catholics to engage.
The pope, an outspoken advocate for refugees and migrants, urged the international community to set aside its differences and turn its attention to crises around the world.
Priests who sexually abuse children are like Judas Iscariot, the disciple who betrayed Jesus Christ, Pope Francis told a gathering of cardinals on Friday.
"At the insistence of the Holy See, we will not be voting" on a standard of conduct and other actions, said Cardinal Daniel DiNardo, president of the U.S. Conference of Catholic Bishops.
In a ceremony at St. Peter's Square in the Vatican, Pope Francis declared the sainthood of the murdered Salvadoran archbishop, the former pontiff and five other people.
The two high-ranking retired clerics, Archbishop Francisco José Cox Huneeus and Bishop Marco Antonio Órdenes Fernández, were expelled from the priesthood because of alleged "manifest abuse of minors."
Two months ago, a Pennsylvania grand jury detailed how Wuerl learned of credible abuse allegations against priests under his supervision — and still gave the men new parish assignments.
Six of 10 U.S. Catholics say Pope Francis is doing only a "fair" or even a "poor" job handling the clergy abuse crisis. He is now only as popular as his predecessor, Pope Benedict.